Structural Basis for Recognizing Phosphoarginine and Evolving Residue-Specific Protein Phosphatases in Gram-Positive Bacteria
Many cellular pathways are regulated by the competing activity of protein kinases and phosphatases.The recent identification of arginine phosphorylation as a protein modification in Accessories bacteria prompted us to analyze the molecular basis of targeting phospho-arginine.In this work, we characterize an annotated tyrosine phosphatase, YwlE, tha